Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 11 - Jul 16
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Pacific Blue Rat Anti-Mouse CD5 Antibody (S-R732)Product Specification Host Rat Antigen CD5 Synonyms T cell surface glycoprotein CD5; Lymphocyte antigen 1 (Ly 1; Lyt 1); Ly 1; Cd5 Location Cell membrane Accession P13379 Clone Number S R732 Antibody Type Rat mAb Isotype IgG2a,k Application FCM Reactivity Ms Positive Sample BALB c mouse splenocytes Purification Protein G Concentration 0. 2 mg ml Conjugation Pacific Blue Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability
Product Specification
| Host | Rat |
| Antigen | CD5 |
| Synonyms | T-cell surface glycoprotein CD5; Lymphocyte antigen 1 (Ly-1; Lyt-1); Ly-1; Cd5 |
| Location | Cell membrane |
| Accession | P13379 |
| Clone Number | S-R732 |
| Antibody Type | Rat mAb |
| Isotype | IgG2a,k |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | BALB/c mouse splenocytes |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Pacific Blue |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Ms |
Background
CD5, also known as T-cell surface glycoprotein CD5 or Leu-1, is a type I transmembrane glycoprotein expressed on the surface of T cells, thymocytes, and a subset of B cells called B-1a cells. It belongs to the scavenger receptor superfamily and has a molecular mass of approximately 67 kDa. CD5 plays a crucial role in modulating immune responses by regulating the activation of T cells and B cells. In T cells, CD5 expression is upregulated upon activation and helps to fine-tune T cell receptor (TCR) signaling, promoting cell survival and non-responsiveness. In B cells, particularly B-1a cells, CD5 helps to prevent overactivation by dampening signals from the B cell receptor (BCR), ensuring that these cells only respond to strong stimuli. The exact ligand for CD5 remains unclear, but it is suggested that it may interact homophilically or with CD72 on B cells.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy